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A: Viagra (sildenafil) is classified as a phosphodiesterase 5 enzyme inhibitor. This metabolite has a PDE selectivity profile similar to sildenafil and an in vitro potency for PDE5 approximately 50% of the parent drug.

I felt slightly light-headed one time after a 150 mg dose. Boshier A, Pambakian N, Shakir SA "A case of nonarteritic ischemic optic neuropathy (NAION) in a male patient taking sildenafil." Int J Clin Pharmacol Ther 40 (2002): 422-3 41. Zrenner E "No cause for alarm over retinal side-effects of sildenafil." Lancet 353 (1999): 340-1 45. In addition to human corpus cavernosum smooth muscle, PDE5 is also found in other tissues including platelets, vascular and visceral smooth muscle, and skeletal muscle, brain, heart, liver, kidney, lung, pancreas, prostate, bladder, testis, and seminal vesicle. As always, talk to your health care provider regarding these interactions and for management of the interactions. 5 percent of people taking Viagra stopped their medicine because of side effects.   (This article covers many, but not all, of the possible side effects with Viagra.

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CYP3A4 Inhibitors Consider a starting dose of 25 mg in patients treated with strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, or saquinavir) or erythromycin. Dilantin could increase the metabolism of the Depakote. Originally developed by scientists in the United Kingdom, it was brought onto the market by Pfizer Inc., a pharmaceutical company in the United States. Sildenafil enhances the effect of NO by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum.

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Viagra exhibits no therapeutic responses in the absence of sexual stimulation. Sildenafil oral tablet is available as the brand-name drugs Viagra and Revatio. Ces nombreux avis sur Viagra pour femme sont disponibles dans notre pharmacie en ligne dans la rubrique dédiée à cet effet et également dans des nombreux forums consacrés à la santé. Stop taking VIAGRA and call your healthcare provider right away if you have any sudden vision loss sudden hearing decrease or hearing loss.

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There are no controlled clinical data on the safety and efficacy of Viagra patients who suffered a myocardial infarction (heart attack), stroke, or life-threatening arrhythmia within the last 6 months. There are possible side effects with Viagra and it is not a bad idea to think twice about taking it. A glass of wine or a single beer is usually fine, but could still have some effect. It can also have side effects including heart attack from low blood pressure. If you can afford to get him an echo cardiogram that will tell the doctor what is going on. In the event of an erection that persists longer than 4 hours, the patient should seek immediate medical assistance. Availability Not every pharmacy stocks this drug. See the end of this leaflet for a complete list of ingredients in VIAGRA.