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Over £50 million unlicensed/counterfeit ED medications have been seized in the last 5 years. Viagra was originally developed by Pfizer but is now off patent and available as a generic. At the end of the long-term study, 88% of patients reported that VIAGRA improved their erections. In fact, some of these side effects (such as high blood pressure) can be attributed to enjoying a healthy sex life as a result of taking Viagra.

When your doctor prescribes a new medication, be sure to discuss all your prescription medications and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as foods you eat. In a study of healthy male volunteers, co-administration of sildenafil at steady state (80 mg t.i.d.) with endothelin receptor antagonist bosentan (a moderate inducer of CYP3A4, CYP2C9 and possibly of CYP2C19) at steady state (125 mg b.i.d.) resulted in a 63% decrease of sildenafil AUC and a 55% decrease in sildenafil Cmax .

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Use In Specific Populations Pregnancy Pregnancy Category B. If Viagra is consumed alongside a meal with a high-fat content, it will take much longer for the medication to work. HOW SUPPLIED Dosage Forms And Strengths VIAGRA is supplied as blue, film-coated, rounded-diamond-shaped tablets containing sildenafil citrate equivalent to 25 mg, 50 mg, or 100 mg of sildenafil.

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If it is not treated right away, priapism can permanently damage your penis sudden vision loss in one or both eyes. The dosimetry was characterized by two independent methods: thermoluminescent dosimeters and radiochromic film.

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Flibanserin (Addyi) was approved by the FDA in 2015 for treatment of FSIAD in premenopausal women. You should be aware never to take more than the recommended Viagra dose without consulting a doctor, and to avoid mixing it with similar PDE5 inhibitors as this can increase the risk of unwanted Viagra side effects. Given sildenafil peak plasma concentrations of approximately 1 μM after recommended doses, it is unlikely that VIAGRA will alter the clearance of substrates of these isoenzymes. Guanylate cyclase stimulators, such as riociguat.