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Also the medication is recommended to be used with caution by patients who have had life-threatening arrhythmias, heart attack, or stroke within the last six months, cardiac failure, coronary artery disease resulting in unstable angina, or by patients with left ventricular outflow obstruction. Also of note is that currently sildenafil has only two Food and Drug-labeled indications and that is for erectile dysfunction or treatment of pulmonary arterial hypertension. For starters, the Food and Drug Administration has approved it only for men (even though some doctors still prescribe it to their female patients, but that's a whole other issue). In addition, N-desmethyl metabolite AUC and Cmax values significantly increased by 200% and 79%, respectively in subjects with severe renal impairment compared to subjects with normal renal function.

Viagra and Alcohol It’s understandable that you may wish to have a drink or two at the same time as taking Viagra, however, it’s important to understand that a combination of the two may impair your ability to perform sexually. Effect of VIAGRA on Blood Pressure When Co-administered with Alcohol VIAGRA (50 mg) did not potentiate the hypotensive effect of alcohol (0. If you suspect you may have overdosed, it is advisable to seek medical help as soon as possible, particularly if you are experiencing unpleasant symptoms or side effects.Q: Is there a less expensive substitute for Viagra? Cerner Multum, Inc. "Australian Product Information." O 0 4. "Product Information.

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Having a large, high-in-fat meal just before you take your Viagra can make it take longer to start working. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Viagra is usually taken only when needed, 30 minutes to 1 hour before sexual activity. I'm a 28 year old mother of two from previous relationships engaged to a 44 year old father of one from a previous marriage. Always keep a current list of the drugs and supplements you take and review it with your healthcare providers and your pharmacist.

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For seniors: The kidneys, liver, or heart of older adults may not work as well as they used to. Doses may range from 5 mg to 20 mg depending on efficacy and patient tolerability. For PAH: Sildenafil works by relaxing the muscles and opening up the blood vessels in your lungs.

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Another thing to consider is that sexual activity is associated with a degree of cardiac risk. Nitric oxide allows the smooth muscles inside the penis to relax, promoting more blood flow to the area during sexual arousal or stimulation. It is eliminated predominantly by hepatic metabolism (mainly CYP3A4) and is converted to an active metabolite with properties similar to the parent, sildenafil. These are lifestyle changes and self-help techniques that any man can do: Avoid heavy and/fatty meals – this means the tablet will take longer to absorb at a lower effect. You will still require approval from the pharmacy in question - this is to ensure your safety - however, this does make obtaining erectile dysfunction medication easier. The dosage for Cialis for once daily use may be increased to 5 mg if necessary. Priapism is a painful erection lasting for more than four hours which requires immediate medical attention and treatment. If it’s not treated right away, this condition can cause permanent damage to your penis. Egan R, Pomeranz H "Sildenafil (Viagra) associated anterior ischemic optic neuropathy." Arch Ophthalmol 118 (2000): 291-2 42. Taking sildenafil with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack. Ask your health care provider for samples or coupons to help with the cost of this medication.